Tracking GLP-1 titration

What titration is and is not

Titration

Adjusting a medication's amount in defined steps, usually upward from a low starting point, according to a schedule set out in the product's labelling and applied by a prescriber to an individual.

Titration exists for a reason: it is how tolerability is managed. That makes the step schedule a clinical instrument, not a user preference — and it is why this site publishes no step values, no intervals and no maximums for any product. Those numbers belong to the prescribing information and to the person who wrote your prescription.

Two objects: the plan and the history

The common failure is a single record that gets edited as things change, leaving no trace of the original plan or of when reality diverged from it.

Keeping them separate is what lets you answer the only interesting question: where did these two diverge, and why?

Recording a titration

1. Enter the plan as scheduled future changes, each with its intended start date, as given to you.
2. Log each injection with the strength printed on the pen or vial — not the strength you assume you are on.
3. Record every change as a dated event, including who instructed it and, where you were told, why.
4. Record holds and step-downs the same way. A pause instructed because of side effects is one of the most valuable entries in the whole log.
5. Never edit past entries to match a new strength. See Wegovy for why this destroys the timeline.

Lining up side effects with steps

The reason to keep exact dates is that the clinical conversation is almost always temporal: did this start after the step-up, and how long did it last? That question is answerable only from timestamped data.

• Record side effects with date and time, and with a consistent severity scale — see logging side effects.
• Keep the same small set of tracked items throughout, so counts are comparable across steps.
• Note the day-of-week relationship to injection day for weekly products; with Ozempic or Zepbound it is often the pattern rather than the incident that matters.
• Export the timeline before an appointment so the discussion starts from a record rather than a recollection.

Supply interruptions and switches

Titration schedules meet reality in the form of shortages, pharmacy substitutions and insurance changes. Each of those is a discontinuity that deserves a record:

• A brand or source change is a new compound with a start date, not a rename.
• A pause of any length is logged explicitly, with its start and end.
• A switch to a compounded product means recording the pharmacy's own concentration and beyond-use date — see compounded GLP-1 medications.
• A restart after a gap is a clinical decision; record what you were instructed rather than resuming where you left off by default.