Peptide reference
Selank
Last reviewed · Written by the PepCycle team
Selank is a synthetic peptide based on tuftsin, a naturally occurring immune-related tetrapeptide, extended with a stabilising Pro-Gly-Pro sequence. It was developed in Russia, where it is registered and has been used as an anxiolytic. It is unapproved in the US, EU and UK and is usually supplied as a nasal solution.
What Selank is
Tuftsin is a four-amino-acid peptide fragment produced from an immunoglobulin, historically studied for its effects on immune cell activity. Selank takes that tetrapeptide and attaches the same Pro-Gly-Pro stabilising tail used in Semax, producing a heptapeptide with improved resistance to breakdown.
It was developed at Russian research institutes and is registered there, where it has been used in anxiety-related indications. Published work has examined effects on anxiety measures and on neurotransmitter and BDNF-related signalling, largely in animal models and in Russian clinical studies.
Forms and variants
- Selank — the base heptapeptide, most often supplied as a nasal solution.
- N-Acetyl Selank amidate — a modified variant marketed as more stable, sometimes abbreviated NA-Selank.
- Lyophilised powder is also sold, intended to be reconstituted into a nasal dropper rather than a syringe.
As with Semax, the practical consequence is that the peptide-tracker default — vial mg, water mL, syringe units — does not fit. What matters is the labelled concentration of the solution and the number of drops or sprays per entry.
What to record
- Variant name (Selank vs N-Acetyl Selank) as part of the compound name.
- Solution concentration as printed, and the bottle or device in use.
- Drops or sprays per entry, with the time of day.
- A new vial record whenever the bottle or device changes, since delivery volume is not standardised.
- Observations with timestamps — for a compound taken for a subjective effect, timestamped notes are the entire dataset.
Status
Selank is unapproved in the US, EU and UK. Its evidence base is largely Russian-language and predominantly preclinical or from smaller clinical studies. Anxiety is also an indication where placebo response is substantial and self-assessment is unreliable — a reason to be cautious about conclusions drawn from an uncontrolled personal log, however carefully kept.
Frequently asked questions
What is Selank derived from?
It is based on tuftsin, a naturally occurring four-amino-acid peptide fragment with immune-signalling roles, extended with a Pro-Gly-Pro sequence that improves stability — the same stabilising approach used in Semax.
Is Selank approved in the US?
No. Selank is registered in Russia but is unapproved in the US, EU and UK, where it is sold only as a research chemical.
How do I track something I take for a subjective effect?
Rate a small, fixed set of things at the same time each day rather than writing occasional free-text notes. Consistency is what makes a self-tracked record readable later — and be aware that an uncontrolled personal log cannot separate an effect from expectation.
Related pages
Track Selank without re-doing the maths
Enter the vial once — mass, diluent volume, lot, date — and every entry after that converts automatically between mcg, mL and syringe units, with the vial counting down as you log.
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